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The Meso Scale Discovery V-PLEX SARS-CoV-2 Panel 2 IgA Kit is a serology assay that detects IgA antibodies to SARS-CoV-2 in human serum and plasma It uses electrochemiluminescence technology and provides quantitative results in under 3 hours The kit includes plates coated with SARS-CoV-2 antigens detection antibodies calibrators controls wash buffers readout buffer and plate seals It has high sensitivity and specificity for detecting recent or prior infection with SARS-CoV-2 This assay aids in understanding immune response and tracking infection rates
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The Meso Scale Discovery V-PLEX Human IL-17D Kit is an electrochemiluminescent immunoassay for quantifying human interleukin 17D (IL-17D) in various biological fluids It uses MSD s SULFO-TAG labels and multi-array technology for sensitive IL-17D measurement with detection limits from 0 03 to 2500 pg/mL The kit includes a 96-well plate detection antibody calibrators and necessary reagents The V-PLEX platform offers a no-wash protocol and results in 3 5 hours enabling high-throughput quantification of this cytokine
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The Meso Scale Discovery COVID-19 Respiratory Panel 1 IgG Assay Kit is an electrochemiluminescent immunoassay that detects IgG antibodies to SARS-CoV-2 in human serum and plasma This qualitative assay can aid in identifying individuals with an adaptive immune response to SARS-CoV-2 indicating recent or prior infection The kit includes a 96-well plate coated with SARS-CoV-2 antigen detection antibody read buffer sample diluent calibrators and controls Results are analyzed on the MSD discovery workbench after a 2-hour incubation This assay has high sensitivity and specificity for SARS-CoV-2 IgG antibodies
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The K15665U-4 is a high-performance low-noise amplifier from Mesoscale It operates from DC to 4 GHz and provides a minimum gain of 15 dB The amplifier has excellent input and output return loss greater than 10 dB and very low noise figure of 2 2 dB at 2 GHz It requires a single positive 5V supply and draws 85 mA of current The amplifier comes in a compact surface mount 4 x 4 mm QFN package Key features include wide bandwidth high gain low noise figure and small footprint ideal for space-constrained designs
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The V-PLEX Plus Human ProInflam Panel I 4-plex Kit from Meso Scale Discovery is a multiplex immunoassay measuring human IFN- IL-1 IL-6 and TNF- in serum plasma and culture supernatants This electrochemiluminescent assay uses MSD s SULFO-TAG labels and multi-array plate technology for sensitive reproducible results from small samples The 4-plex panel efficiently quantifies proinflammatory cytokines aiding immunology inflammation and drug discovery research The kit includes a 96-well plate detection antibodies read buffer calibrators and protocols for assay optimization and data analysis
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An alkaloid active against the F32 chloroquine-sensitive (IC50 0 52 UM) and FcB1 and FcM2 chloroquine-resistant strains of P falciparum (IC50s 0 52 0 8 and 0 49 UM respectively) and reduces parasitemia in a mouse model of P vinckei infection (ED50 18 9 mg/kg per day) decreases LPS-induced increases in TNF-a IL-1B and IL-6 levels and p65 nuclear translocation in RAW 264 7 cells at 5 UM decreases serum levels of IL-10 TNF-a and IL-6 and reduces mortality in a mouse model of LPS-induced endotoxemia inhibits proliferation of various cancer cells (IC50s 2 65-370 ng/ml) induces apoptosis and decreases STAT3 phosphorylation in HSC3 and HSC4 oral cancer cells from 0 1-10 UM and reduces tumor growth in an HSC3 mouse xenograft model at 10 mg/kg per day for 24 days
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The Meso Scale Discovery V-PLEX Human IL-6 Kit is a highly sensitive and quantitative assay for measuring human interleukin 6 (IL-6) in serum plasma and cell culture supernatants This electrochemiluminescent immunoassay utilizes MSD s proprietary SULFO-TAG labels and multi-array technology to enable simultaneous detection of IL-6 down to 0 05 pg/mL with an upper limit of 10 000 pg/mL The kit includes a 96-well plate pre-coated with capture antibody detection antibody conjugated to ruthenium calibrators and reagents for 50 tests It provides accurate reproducible quantitation of IL-6 levels with high sensitivity and wide dynamic range
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The Meso Scale Discovery V-PLEX SARS-CoV-2 Panel 2 Mouse IgA Kit is designed to quantitatively measure IgA antibodies specific to SARS-CoV-2 in mouse serum and plasma samples This electrochemiluminescence immunoassay allows high-throughput testing of samples for the presence of IgA antibodies binding to the receptor binding domain (RBD) of the SARS-CoV-2 spike protein The kit includes a plate coated with SARS-CoV-2 RBD antigen detection antibodies calibrators controls buffers and substrate Results are obtained in under 3 hours using an MSD instrument This assay can aid in evaluating vaccine efficacy and immunogenicity in mouse models of COVID-19
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The Meso Scale Discovery V-PLEX Human IL-6 Kit is a highly sensitive and quantitative immunoassay for the detection of human interleukin 6 (IL-6) in cell culture supernatants serum plasma and other biological fluids The kit utilizes electrochemiluminescence technology and provides accurate reproducible results with a lower limit of detection of 0 05 pg/mL and an upper limit of 10 000 pg/mL The assay requires 50 L or less sample volume and can be read on the MSD QuickPlex SQ 120 MESO SECTOR S 600 or MESO QuickPlex SQ 120 instruments The kit includes a plate coated with capture antibody detection antibody Read Buffer Diluent 2 Calibrator Diluent and lyophilized calibrator
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The V-PLEX SARS-CoV-2 Panel 34 IgG Kit from Meso Scale Diagnostics is an immunoassay that quantitatively measures IgG antibodies to SARS-CoV-2 in human serum and plasma This kit includes a 96-well plate coated with recombinant SARS-CoV-2 antigen detection antibody assay diluent calibrator and controls It can detect IgG antibodies to the SARS-CoV-2 spike and nucleocapsid proteins with high sensitivity and specificity The electrochemiluminescence immunoassay format provides a fast and efficient workflow with results in under 3 hours This assay aids in understanding past exposure to SARS-CoV-2 and immune response
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